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KMID : 1001920190620030328
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Journal of Korean Neurosurgical Society
2019 Volume.62 No. 3 p.328 ~ p.335
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Epilepsy Surgery in Children versus Adults
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Lee Ki-Hyeong
Lee Yun-Jin
Seo Joo-Hee
Baumgartner James E.
Westerveld Michael
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Abstract
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Epilepsy is one of the most common chronic neurological disorder affecting 6?7 per 1000 worldwide. Nearly one-third of patients with newly diagnosed epilepsy continue to have recurrent seizures despite adequate trial of more than two anti-seizure drugs : drug-resistant epilepsy (DRE). Children with DRE often experience cognitive and psychosocial co-morbidities requiring more urgent and aggressive treatment than adults. Epilepsy surgery can result in seizure-freedom in approximately two-third of children with improvement in cognitive development and quality of life. Understanding fundamental differences in etiology, co-morbidity, and neural plasticity between children and adults is critical for appropriate selection of surgical candidates, appropriate presurgical evaluation and surgical approach, and improved overall outcome.
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KEYWORD
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Epilepsy, Surgery, Drug resistant epilepsy, Child
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